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Fırat Tıp Dergisi |
2017, Cilt 22, Sayı 3, Sayfa(lar) 143-145 |
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Oral Isotretinoin Induced Pigmentation Disorder: A Case Report |
Betül DEMİR1, Demet ÇİÇEK1, Leyla BİLİK1, Ebru GÜLER AYDOĞDU2, Hakan ARTAŞ3, Nida DEMİRPOLAT4, Can ERGİN5 |
1University of Firat School of Medicine, Dermatology Department, Elazig, Türkiye 2Elazig Education and Research Hospital, Clinic of Dermatology, Elazig, Türkiye 3University of Firat School of Medicine, Department of Radiology, Elazig, Türkiye 4University of Firat School of Medicine, Department of Otolaryngology, Elazig, Türkiye 5Diskapi Yildirim Beyazit Education and Research Hospital, Clinic of Dermatology, Ankara, Türkiye |
Hyperpigmentation, which develops secondary to drugs, is generally due to the accumulation of the drugs on the skin. Isotretinoin is synthetic deriva-tive of vitamin A and it is the 13-cis retinoic acid form of a retinoid. A 20-year-old female patient presented to the dermatology outpatient clinic with complaints of brown stains on the nose. The medical history also revealed that the patient had been using isotretinoin 30 mg/day for the last six months for acne and no other oral or topical drug use was present. Her dermatological examination revealed that a gray macule of 1x1 cm was present in the left nasal wing. The dermatoscopic examination of the lesion revealed thin, gray, pigmented structures in particular, surrounding the follicular openings. The absence of pigmentation defects due to systemic isotretinoin use in the literature review has led us to present the current case.
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