The Horseshoe kidney is the most common fusion anomaly and its incidence is around 1/400. It is two times more common in males than females. Because of the urinary stasis due to the higher location of the ureteropelvic junction in horseshoe kidney, the incidence of kidney stones is high. In this study we aimed to present a laparoscopic pyelolithotomy case performed after a failed ESWL treatment in a kidney stones patient with a horseshoe kidney.