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Fırat Tıp Dergisi
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Frequency of Celiac Disease in Children with Idiopathic Epilepsy
Derya ALTAY1, Hatice Gamze POYRAZOĞLU2, Yaşar DOĞAN1
1Fırat Üniversitesi Tıp Fakültesi, Çocuk Gastroenteroloji Bilim Dalı, Elazığ, Türkiye
2Fırat Üniversitesi Tıp Fakültesi, Çocuk Nöroloji Bilim Dalı, Elazığ, Türkiye

Objective: One of the extra-intestinal findings of celiac disease is epilepsy. In this study, it was aimed to determine the prevalence of celiac disease in children investigated for idiopathic epilepsy.

Material and Method: In this study, pediatric patients with a complaint of seizure who admitted to the Pediatric Neurology Department of Fırat University Hospital were included between June 2016 and March 2017. Serum anti tissue-transglutaminase IgA and IgA levels were measured in all patients, diagnosis of celiac disease was confirmed by duodenal biopsy if anti tissue-transglutaminase IgA positivity was detected.

Results: A total of 109 epileptic patients were included in this study. Mean age of the patients were 8.61+4.67 years and 57 (52.3%) patients were male gender. All cases had normal serum IgA levels. Serum antitissue-transglutaminase IgA positivity was detected in only one case (0.91%) and the duodenal biopsy of this patient was Marsh 3b.

Conclusion: Patients diagnosed with idiopathic epilepsy should be questioned for celiac disease symptoms and screened if necessary.


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