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Fırat Tıp Dergisi
2020, Cilt 25, Sayı 3, Sayfa(lar) 135-139
[ Turkish ] [ Tam Metin ] [ PDF ]
Is Nonalcoholic Fatty Liver Diease A Risk Factor for Recurrent Acute Pankreatitis?
Orkide KUTLU1, Yılmaz BİLGİÇ2, Evren BAHRİ3, Yahya ATAYAN4, Yasir Furkan ÇAĞIN2
1Okmeydanı Eğitim ve Araştırma Hastanesi, İç Hastalıkları Kliniği, İstanbul, Türkiye
2İnönü Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Gastroenteroloji Bilim Dalı, Malatya, Türkiye
3İnönü Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Endokrinoloji Bilim Dalı, Malatya, Türkiye
4Malatya Eğitim ve Araştırma Hastanesi, İç Hastalıkları Kliniği, Malatya, Türkiye

Objective: Acute pancreatitis (AP) is an auto-digestive,inflammatory disease of the pancreas while recurrent episodes of acute pancreatitis can be seen in about a quarter of patients. The aim of this study was to investigate whether non- alcoholic fatty liver disease (NAFLD) association is different from AP patients in patients with recurrent acute pancreatitis (RAP).

Material and Method: Patients who were admitted to gastroenterology clinic with the preliminary diagnosis of AP between 2014-2017 were scree-ned retrospectively. A total of 428 patients with non-alcohol related AP, according to Atlanta criteria, were included in the study. Forty patients with multiple episodes were defined as RAP. Patient groups included age, gender, white blood cell, hemoglobulin, platelet, AST, ALT, ALP, GGT, total bilirubin, direct bilirubin, calcium, TG measurements; gall bladder operation, ERCP status, liver USG and pancreatic USG reports were compared statistically.

Results: In patients with AP grade I, II and III rates of steatosis were 8%, 10.8% and 14.6% respectively; and in 66.6% steatosis was not detected. In patients with RAP, grade I, II and III rates were 5%, 12.5% and 10% respectively and in 72.5% steatosis was not detected. TG values (p =0.002) and ERCP status (p = 0,003) were significantly different in RAP group. There was no statistically significant difference for hepatosteatosis in hepatobili-ary USG when AP and RAP groups were compared (p = 0.761).

Conclusion: In our study, the prevalence of NAFLD in patients with RAP was similar to that in AP patients. In order to clarify the role of NAFLD in the etiology of AP recurrences, new studies will be needed.


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