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Fırat Tıp Dergisi
2021, Cilt 26, Sayı 1, Sayfa(lar) 043-047
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Evaluation of Factors Affecting Biochemical Recurrence After Radical Prostatectomy in Localized Prostate Cancer
Cavit CEYLAN1, Samet ŞENEL1, İbrahim KELEŞ2
1Ankara Türkiye Yüksek İhtisas Eğitim ve Araştırma, Üroloji Kliniği, Ankara, Türkiye
2Afyon Kocatepe Üniversitesi Tıp Fakültesi, Üroloji Anabilim Dalı, Afyon, Türkiye

Objective: We aimed to analyze risk factors affecting biochemical recurrence rate after radical prostatectomy in localized prostate cancer, retrospectively.

Material and Method: The factors affecting biochemical recurrence were evaluated retrospectively in 84 patients who underwent open retropubic radical prostatectomy for localized prostate cancer in our clinic between March 2009 and February 2019. Preoperative PSA values, risk groups according to the D\'Amico risk classification, body mass indexes, age and postoperative Gleason scores were recorded. PSA value for biochemical recurrence was accepted as 0.2 ng/ml and above in two consecutive measurements. It was investigated whether these factors are related to biochemical recurrence or not.

Results: Biochemical recurrence was detected in 17 patients (20.2 %) and wasn’t detected in 67 (79.8 %) patients. There was no significant difference between biochemical recurrence rates in patients with low-risk and intermediate-high risk localized prostate cancer (p =0.251). Preoperative PSA and Gleason scores were statistically different in these patients (p =0.034 and p =0.023 respectively).

Conclusion: We found that preoperative PSA and postoperative Gleason score were significant as a parameter affecting biochemical recurrence in localized prostate cancer. Patient follow-up should be done according to the D\'Amico risk groups considering the guidelines, but it should not be overlooked that the follow-up should be individualized if necessary.


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