Objective: To share our data and experiences of the primary and recurrent advanced larynx tumors.

Material and Method: Recordings of patients which have undergone total laryngectomy between 2012-2019, for reccurence after primary radiotherapy is reviewed retrospectively. Patients were reviewed for age, gender, T stage, primary site of disease, transglottic extension, lymph node metastasis, extracapsular extension, whether thyroid gland excision is done and 5-year disease free survival rate.

Results: Total laryngectomy is done in 81 patients of whom 60 (74%) were primary and 21 (26%) were recurrence cases after radiotherapy. Eighteen of the primary patients had metastatic lymph nodes, 15 patients had thyroid lobectomy and 7 patients had total thyroidectomy. The 5-years diseasefree survival rates were 58.3% in primary patients and 52.9% in salvage patients.

Conclusion: Performing total laryngectomy after radiotherapy recurrence may cause additional comorbidities in the patient compared to the primary patients. We are in the consideration that, when making a choose between surgery and radiotherapy, the final decision should be made with patients by informing them about possible recurrences and secondary surgeries due to these recurrences in addition to the side effects of radiotherapy.