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Fırat Tıp Dergisi
2004, Cilt 9, Sayı 4, Sayfa(lar) 120-122
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Plasma Levels of Lipoprotein (a) in Behcet’s Disease as a Risk Factor of Thrombotic and Atherosclerotic
Başak COŞKUN1, Yunus SARAL1, Ahmet GÖDEKMERDAN2, Arzu ATASEVEN1, Naci COŞKUN3
1 Fırat Üniversitesi Tıp Fakültesi Dermatoloji Anabilim Dalı, ELAZIĞ
2 Fırat Üniversitesi Tıp Fakültesi İmmünoloji Anabilim Dalı, ELAZIĞ
3 Fırat Üniversitesi Tıp Fakültesi Kardiyoloji Anabilim Dalı, ELAZIĞ

Objective: Plasma levels of lipoprotein (a) (Lp(a)) were investigated in patients with Behcet’s disease and controls in order to asses its role in thrombotic and atherosclerotic complications of this disease and of disease activity.

Material and Methods: The study included 40 patients with Behcet’s disease, 30 healty volunteers. One of the patient had active and three of them had a history of thrombotic complications.

Results: Plasma Lp(a) and other acute phase reactant levels were significantly higher in the study group than in the controls. There was no difference between the groups with and without thrombotic complications for any of these measurements.

Conclusions: Plasma Lp(a) levels were significantly higher in the active patients than inactive patients, it might be a risk factor of disease activity in Behcet’s disease. Lp(a) is an important risk factor for development of coronary artery disease. However, further studies are needed to show the thrombogenic role of Lp(a). © 2004, Fırat Üniversitesi, Tıp Fakültesi.


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