Objectives: We aimed to determine the efficacy of tamsulosin (0.4 mg/day) as oral expulsive medical therapy in patients who were followed for distal üreter calculi at urology clinic in Elazig Public Hospital.

Material and Methods: The study was continued with 102 consecutive patients; 21 female and 30 male was included in Group A (51) with a mean age of 37.2±12.6 (16-62y) and 19 female and 32 male was included in Group B (51) with a mean age of 35.5±11.7 (17-63y). Group A consisted control patients treated with conservative therapy (analgesic, antiemetic), Group B included study patients treated with oral expulsive medical therapy (tamsulosin 0.4 mg/gün) and they were followed 28 days. 30 mg /day deflazacort, lansaprozole 30 mg/day and 2x500 mg /day cinolone with minimal side effects were performed to the groups maximum 10 days. To drink minimum 2 liters of water per a day was offered to all of the patients, 75 mg diclofenac sodium (1.2mg/kg) was performed intramusculary as analgesic when required. Patients who were Stone-free was excluded from the study in Group A and B. The pass of the stones and drug’s side effects were questionaired to the patients at weekly controls.

Results: Results and Conclusion: In Group A, 19 patients (37.2%) expulsed stone meanly at 18.1±7.3 days, in Grup B, 40 patients (78.4%) expulsed stone meanly at 5.8±2.7 days.

Conclusion: In conclusion, oral expulsive medical therapy can be an approach that must be thought in urether lower stones after the evaluation of the patient exactly. ©2007, Firat University, Medical Faculty