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Fırat Tıp Dergisi
2009, Cilt 14, Sayı 3, Sayfa(lar) 204-206
[ Turkish ] [ Tam Metin ] [ PDF ]
Reciprocal Translocation T(1;5)(P33;Qter) in aq Oligospermic Infertile Male
Deniz EROL, Hüseyin YÜCE
Fırat Üniversitesi Tıp Fakültesi, Tıbbi Biyoloji Anabilim Dalı, ELAZIĞ, Türkiye

Infertility affects an estimated 15% of couples and in roughly half of cases male-related factors are involved, frequently associated with impaired spermatogenesis, e.g. oligospermia or azoospermia. The incidence of somatic chromosome anomalies in infertile male patients hase been reported between 2.2 and 19.6%. In this study, we present the results of a cytogenetic analysis performed on a couple, who were referred to our laboratory due to infertility. We found a normal karyotype (46,XX) in female, and balanced reciprocal translocation [46,XY,t(1;5)(p33;qter)] in the male. We deduced that chromosomal rearrangements in this case were caused infertility due to the interference with spermatogenesis.

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