Objective: This study aimed to evaluate the factors affecting the spiritual well-being and quality of life of older adults living in nursing homes.

Material and Method: This crosssectional study involved 188 older adults living in nursing homes in Manisa province.

Results: The mean total spiritual well-being of older adults was 30.86 ± 6.70. A statistically significant difference was found between the EQ-5D quality of life scale, mobility, self-care, usual activities, pain/discomfort, anxiety/depression subdimensions, and general health perception.

Conclusion: It was determined that the poor health perception of the elderly negatively affects their quality of life and spiritual well-being.