Objective: Kidney injury molecule 1(KIM-1) is a transmembrane glycoprotein that indicates kidney damage and has been shown to be associated with chronic inflammation. Atherosclerosis is a chronic inflammatory disease affecting medium and large arteries. Acute myocardial infarction is an important clinical presentation responsible for the morbidity and mortality of atherosclerotic cardiovascular disease. There is little information in the literature about KIM-1 levels in patients with acute myocardial infarction. The aim of this study is to examine KIM-1 levels in patients with acute myocardial infarction.

Material and Method: Patients with acute myocardial infarction (patient group) and patients with normal coronary arteries detected by coronary angiography (control group) were included in the study. KIM-1 level was determined by ELISA method in the serum taken before angiography. The prevalence of coronary artery disease was determined by calculating the SYNTAX score and Gensini scores.

Results: Seventy-eight patients diagnosed with acute myocardial infarction and 53 patients with normal coronary arteries were included in the study. Median KIM-1 level was found to be similar in both groups (Patient group and control group median values; 55.82, 54.45, p >0.05). Similarly, no statistically significant relationship was observed between the Gensini score and Syntax score, which indicate the severity and prevalence of coronary artery disease, and the KIM-1 level (correlation coefficient and p values; -.012, p >0.05 and -.041, p >0.05, respectively).

Conclusion: Serum KIM-1 levels are similar in patients with acute myocardial infarction and those with normal coronary arteries. There is no relationship between serum KIM-1 levels and the prevalence of coronary artery disease.