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Fırat Tıp Dergisi
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Maternal and Perinatal Outcomes of Pregnancies Complicated with Severe Preeclampsia, Eclampsia and HELLP Syndrome
Mehmet BAYRAK1, Kemal GÜNGÖRDÜK3, Gökhan YILDIRIM2, Ali TEKİRDAĞ2
1Bursa Şehir Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, Bursa, Türkiye
2İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, Türkiye
3Muğla Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, Muğla, Türkiye

Objective: The aim of our study is to determine the maternal and perinatal morbidity and mortality rates of patients with severe preeclampsia, ec-lampsia and HELLP syndrome and to compare them with the literature data.

Material and Method: The data of the patients who were followed up with the diagnosis of severe preeclampsia, eclampsia and Hellp syndrome for two years and recorded in the electronic data information system were analyzed retrospectively.

Results: During the study period 33719 delivery was occurred in our hospital. The preeclampsia, eclampsia and HELLP syndrome rate were found as 1.2% (n =407), 0.12% (n =41) and 0.2% (n =65) respectively. Maternal age, gravidity and parity were found to be higher in the HELLP syndrome group than in the severe preeclampsia and eclampsia groups. Women in the eclampsia group were more likely to deliver by Caesarean section than those in the HELLP syndrome and severe preeclampsia groups (80.5%, 75.4%, 68.8%, respectively) (p =0.005). The rates of adverse maternal outco-mes for women in the HELLP syndrome and eclampsia groups were higher than the rates of adverse maternal outcomes in the severe preeclampsia group (13.8%, 12.2%, 4%, respectively) (p <0.0001). Acute renal failure (ARF) was the most common adverse outcome. ARF was most common in the HELLP syndrome group (10.8%). No significant difference in neonatal morbidity and perinatal mortality were found among the three groups.

Conclusion: This study demonstrates that pregnancies complicated with HELLP syndrome and eclampsia have a significiantly higher frequency of maternal morbidity than pregnancies with severe preeclampsia. Correct diagnosis and timely intervention can decrease the risk of maternal and perina-tal morbidity and mortality.


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