Objective: Streptococcus agalactiae is a serious invasive infectious agent that can be colonized in gastrointestinal and genitourinary system in he-althy individuals, and may cause high mortality in newborns, pregnant women and those with underlying disease. In this study, it was aimed to inves-tigate the growth rates of S. agalactiae isolated from urine cultures and to determine their antibiotic susceptibility.

Material and Method: S. agalactiae isolates recovered from urine cultures between June 2016 and April 2019 were investigated retrospectively. Conventional methods were used for the identification. Antibiotic susceptibility tests were performed and evaluated according to Clinical and Labora-tory Standards Institute recommendations.

Results: S. agalactiae was detected as a single agent in 163 (0,30%) of 54.009 urine cultures. In total, S. agalactiae was isolated in 29 (0,14%) of 19.794 male patients 134 (0,39%) of 34.215 female patients. Among female patients, 18 (0,62%) of 2.883 were pregnant. It was determined that 95% of the patients were outpatients and 35% were from the Obstetrics and Gynecology Unit. The isolates were 100% sensitive to penicillin, ampicillin, cefotaxime and vancomycin; while 10,6% of the strains were resistant to erythromycin and 24,3% of the strains were resistant to to ofloxacin.

Conclusion: S. agalactiae is less frequently isolated from urinary tract infections. Prophylaxis and treatment are recommended especially for risk group. In our study, the increased resistance rates of erythromycin and ofloxacin is notable. Routinely follow-up of S. agalactiae isolation from clini-cal samples, especially from urine cultures, evaluation of the clinical symptoms of patients (particularly in pregnant and/or people with underlying diseases) and monitor antibiotic resistance for early and appropriate treatment are important.