Objective: Although poisonings are common in childhood, they are usually asymptomatic and/or with mild symptoms. Life-threatening situations are rarely encountered. Our study aimed to identify the poisoning patients treated in pediatric intensive care and evaluate the treatment process.

Material and Method: All patients aged 1 month to 18 years treated in pediatric intensive care between January 2017-August 2022 were included. Those treated in the emergency department who did not take toxic doses, and were not aged from 1 month-18 to year were excluded from the study. Data were obtained retrospectively from electronic and/or archive files. The relationship between poisoning type, accidental occurrence, and antidote use and \'Pediatric Risk of Mortality III\' (PRISM III); type of poisoning by age, gender, and accidental occurrence, investigation of substance, drug poisoning, clinical and laboratory effects were evaluated.

Results: In our study, 81(2.83%) of total 2860 patients; 33(40.74%) male and 48(59.26%) female patients were included. The median of PRISM III was 3.00, and length of stay was 2.00. The mortality rate was 1(1.23%) patient. 66(81.48%) patients were drug intoxication. Accidental poisoning was 57(70.37%) and suicidal was 24(29.63%). While the antidote was not given to 69(85.19%) patients, antidote support was given to 12(14.81%) of them. The relationship between the status of antidote use and higher PRISM III score is significant (p =0.006). The average age of those who were accidentally poisoned was younger than those who were suicidal. The rate of poisoning for suicidal purposes in girls is higher than in boys (girls/boys:41.67%/12.12%). Age (p <0.001) and gender (p =0.004) were found to be statistically significant in the relationship between age and gender in accidental poisonings. In poisonings; 15(18.52%) patients were exposed to substances and 66(81.48%) drugs.

Conclusion: Poisoning is an important and preventable cause of mortality. The type of poisoning, type and amount of exposure, the time after exposure, age of the child are important for treatment and prognosis. When the fatality risk of poisoning is high, patients should be treated in pediatric intensive care.